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Antigenic Specificity | Human Angiopoietin-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
Immunogen | Immunogen: Recombinant human Angiopoietin-2 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7017 / sc-7016 / sc-7015 / sc-20718 |
Other Names | [angiopoietin-2 isoform b; Angiopoietin-2; angiopoietin-2; angiopoietin 2], [ANGPT2; ANGPT2; ANG2; AGPT2; ANG-2] |
Gene, Accession # | [ANGPT2], Gene ID: 285, NCBI: NP_001112359.1, UniProt: O15123 |
Catalog # | MBS1489386 |
Price | $160, $235 |
Order / More Info | Human Angiopoietin-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |