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Antigenic Specificity | ORAI3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. ORAI3 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents |
Immunogen | Immunogen: ORAI3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human ORAI3. Buffer: ORAI3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ORAI3; TMEM142C; TMEM142C; Protein orai-3; Transmembrane protein 142C; ORAI calcium release-activated calcium modulator 3], [ORAI3; ORAI3; TMEM142C; TMEM142C] |
Gene, Accession # | [ORAI3], Gene ID: 93129, NCBI: Q9BRQ5.2, UniProt: Q9BRQ5 |
Catalog # | MBS150836 |
Price | $375 |
Order / More Info | ORAI3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |