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Antigenic Specificity | Seladin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Seladin 1 antibody detects endogenous levels of Seladin 1. Function: Catalyzes the reduction of the Delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.Similarity: Belongs to the FAD-binding oxidoreductase/transferase type 4 family. |
Immunogen | Immunogen: A synthesized peptide derived from human Seladin 1. Subcellular Location: Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Tissue Specificity: Highly expressed in brain and adrenal gland with moderate expression in liver, lung, spleen, prostate and spinal cord. Low expression in heart, uterus and prostate. Undetectable in blood cells. In the brain, strongly expressed in cortical regions, substantia nigra, caudate nucleus, hippocampus, medulla oblongata and pons. In brains aff |
Other Names | [24 dehydrocholesterol reductase; 24-dehydrocholesterol reductase; 3 beta hydroxysterol delta 24 reductase; 3-beta-hydroxysterol delta-24-reductase; DCE; Delta(24)-sterol reductase; Desmosterol to cholesterol enzyme; DHC24_HUMAN; Dhcr24; Diminuto dwarf1 homolog; Diminuto/dwarf1 homolog; KIAA0018; Nbla03646; Seladin-1; Selective AD indicator 1; Selective Alzheimer's Disease Indicator 1] |
Gene, Accession # | [SELADIN1], Gene ID: 1718, NCBI: NP_055577.1, UniProt: Q15392 |
Catalog # | MBS9603700 |
Price | $240, $280 |
Order / More Info | Seladin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |