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Antigenic Specificity | Glutaminyl-peptide cyclotransferase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Glutaminyl-peptide cyclotransferasepolyclonal antibody. Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. |
Immunogen | Immunogen: Recombinant Human Glutaminyl-peptide cyclotransferase protein |
Other Names | [Glutaminyl cyclase Glutaminyl-tRNA cyclotransferase Glutamyl cyclase QPCT] |
Gene, Accession # | Gene ID: 25797, NCBI: NP_036545.1, UniProt: Q16769 |
Catalog # | MBS9415284 |
Price | $320 |
Order / More Info | Glutaminyl-peptide cyclotransferase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |