Bik Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBik
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionApoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such protein BIK was recently identified as an endoplasmic reticulum (ER)-residing pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family that stimulates mitochondrial release of cytochrome c following p53 induction of apoptosis. A significant fraction of BIK is found as an ER transmembrane protein, with most of the protein facing the cytosol. Restricting BIK to the ER membrane by replacing the transmembrane region with that of the ER-
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide from near the amino terminus of human BIK.
Other Names[Bcl-2-interacting killer, apoptosis inducer NBK]
Gene, Accession #[Bik], Gene ID: 638, NCBI: CAG30276, UniProt: Q13323
Catalog #MBS9403126
Price$320
Order / More InfoBik Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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