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Antigenic Specificity | Neuronal Cell Adhesion Molecule (NRCAM) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse, and rat NRCAM. The NRCAM gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Fusion protein corresponding to aa 30-845 (extracellular domain) of mouse NRCAM. This sequence is 96% identical in rat, 91% identical in human, and ~50% identical in Neurofascin. |
Other Names | [neuronal cell adhesion molecule isoform 2; Neuronal cell adhesion molecule; neuronal cell adhesion molecule; neuronal cell adhesion molecule; Neuronal surface protein Bravo; mBravo; NgCAM-related cell adhesion molecule; Ng-CAM-related], [Nrcam; Nrcam; Bravo; mKIAA0343; C030017F07Rik; C130076O07Rik; Kiaa0343; Nr-CAM; mBravo; Ng-CAM-related] |
Gene, Accession # | [NRCAM], Gene ID: 319504, NCBI: NP_001139503.1, UniProt: Q810U4 |
Catalog # | MBS191365 |
Price | $410 |
Order / More Info | Neuronal Cell Adhesion Molecule (NRCAM) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |