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Antigenic Specificity | TGF-alpha (Transforming Growth Factor alpha) |
Clone | [SPM357] |
Host Species | Mouse |
Reactive Species | human, cow, rat, mouse. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF? +/- (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. |
Immunogen | Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFa Cellular Localization: Cytoplasmic and Extracellular (secreted) |
Other Names | [EGF-like TGF; ETGF; TFGA; TGF Type 1; TGFA; Wa1; Waved 1] |
Gene, Accession # | [TGFA], Gene ID: 7039, NCBI: NP_001093161.1, UniProt: P01135 |
Catalog # | MBS4380249 |
Price | $190, $340, $340 |
Order / More Info | TGF-alpha (Transforming Growth Factor alpha) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kobrin MS et. al. J Bio Chem, 1986, 261:14414-9. Kudlow JE et. al. Endocrinology, 1987, 121(4):1577-9. Kobrin MS et. al. Endocrinology, 1987, 121(4):1412-6. Kudlow JE et. al. J Bio Chem, 1989, 264(7):3880-3 |