CYP3A4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CYP3A4 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CYP3A4 antibody detects endogenous levels of total CYP3A4. Description: This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 |
| Immunogen | Immunogen: Purified recombinant fragment of human CYP3A4 expressed in E. Coli Subcellular Location: Endoplasmic Reticulum Membrane. Microsome Membrane. Tissue Specificity: Expressed in prostate and liver. According to some authors, it is not expressed in brain (PubMed:19094056). According to others, weak levels of expression are measured in some brain locations (PubMed:19359404 and PubMed:18545703). Also expressed in epithelium of the small intestine and large intestine, bile duct, nasal mucosa, |
| Other Names | [1, 8-cineole 2-exo-monooxygenase; Albendazole monooxygenase; Albendazole sulfoxidase; CP33; CP34; CP3A4_HUMAN; CYP3; CYP3A; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 3A4; Cytochrome P450 family 3 subfamily A polypeptide 4; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450 subfamily IIIA polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; Cytochrome P450-PCN1; Glucocorticoid inducible P450; HLP; MGC126680; NF 25; NF25; Nifedipine oxidase; P450 III steroid inducible; P450 PCN1; P450, family III; P450C3; P450PCN1; Quinine 3 monooxygenase; Quinine 3-monooxygenase; Taurochenodeoxycholate 6 alpha hydroxylase; Taurochenodeoxycholate 6-alpha-hydroxylase] |
| Gene, Accession # | [CYP3A4], Gene ID: 1576, NCBI: NP_001189784.1, UniProt: P08684 |
| Catalog # | MBS9602493 |
| Price | $235, $295, $370 |
| Order / More Info | CYP3A4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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