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Antigenic Specificity | Amyloid Beta Peptide 42 |
Clone | [CA9 10C11] |
Host Species | Mouse |
Reactive Species | human, other primates, mouse, rat. The antibody does not cross react with amyloid beta peptide 40 in dot blotting and ELISA. cross-reactivity to amyloid beta peptide 43 is less than 1% in ELISA. |
Isotype | IgG2b,k |
Format | biotin conjugate |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes the C-terminal sequence (MVGGVVIA) of Abeta42 and full length Abeta42. Description: Biotin conjugated mouse monoclonal antibody to C-terminal of amyloid beta peptide 42 (Abeta42) background: Amyloid beta peptide 42 (Abeta42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer's disease. Abeta42 and Abeta40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Abeta42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Abeta42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Abeta42 contributes to the pathogenesis of Alzhei |
Immunogen | Immunogen: KLH conjugated to a short peptide (MVGGVVIA) with amino acid sequence corresponding to the C-terminal of Abeta42. Myeloma: Sp2/0-Ag14. Light Chain: Kappa |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS592380 |
Price | $475 |
Order / More Info | Amyloid Beta Peptide 42 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |