Cullin 1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Cullin 1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cullin-1(CUL1) detection. Tested with WB in Human;Mouse;Rat. Background: Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1. |
| Immunogen | Immunogen: E Coli-derived human Cullin 1 recombinant protein (Position: E457-D770). Human Cullin 1 shares 100% amino acid (aa) sequence identity with mouse Cullin 1. Ig Type: Rabbit IgG |
| Other Names | [Cullin-1; CUL 1; CUL-1; CUL1; CUL1_HUMAN; Cullin-1; Cullin1; MGC149834; MGC149835; cullin 1], [CUL1; CUL1; CUL-1] |
| Gene, Accession # | Gene ID: 8454, NCBI: NP_003583.2, UniProt: Q13616 |
| Catalog # | MBS177900 |
| Price | $280 |
| Order / More Info | Cullin 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kipreos ET, Lander LE, Wing JP, et al. (1996). cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.. Cell 85 (6): 829-39. Bonaldo MF, Lennon G, Soares MB (1997). 2. Michel, J. J., Xiong, Y. Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 9: 435-449, 1998. 3. Normalization and subtraction: two approaches to facilitate gene discovery.. Genome Res. 6 (9): 791-806. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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