Edit |   |
---|---|
Antigenic Specificity | INPPL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | INPPL1, a protein that in addition to the phosphatase domain contains an SH2 (src-homology domain 2) motif. INPPL1 is a member of the family of inositol triphosphate phosphatases. The INPPL1 gene is mapped on 11q13.4. Immunoblot analysis revealed that SHIP2 was widely expressed in fibroblast and nonhematopoietic tumor cell lines, unlike the SHIP protein, which was found only in cell lines of hematopoietic origin. Using human epithelial cell lines and primary human corneal and epidermal keratinocytes, Yu et al. showed that micro RNA-184 (MIR184) interfered with the ability of MIR205 to downregulate expression of SHIP2.SHIP2 may play a significant role in regulation of phosphatidylinositol 3-prime-kinase signaling by growth factors and insuli |
Immunogen | Immunogen: INPPL1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human INPPL1, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit INPPL1; INPPL1; INPPL1; INPPL 1; INPPL-1; INPPL-1; SHIP2; Inositol polyphosphate 5 phosphatase like 1; Inositol polyphosphate phosphatase like 1; INPPL 1; INPPL1] |
Gene, Accession # | [INPPL1] |
Catalog # | MBS5313037 |
Price | $345 |
Order / More Info | INPPL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |