EFHD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEFHD2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionEFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κB-activating branch.
ImmunogenImmunogen: EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. Buffer: EFHD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[EFHD2; SWS1; SWS1; EF-hand domain-containing protein D2; Swiprosin-1; EF-hand domain family, member D2], [EFHD2; EFHD2; SWS1; SWS1]
Gene, Accession #[EFHD2], Gene ID: 79180, NCBI: NP_077305, UniProt: Q96C19
Catalog #MBS150334
Price$375
Order / More InfoEFHD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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