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Antigenic Specificity | EFHD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κB-activating branch. |
Immunogen | Immunogen: EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. Buffer: EFHD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [EFHD2; SWS1; SWS1; EF-hand domain-containing protein D2; Swiprosin-1; EF-hand domain family, member D2], [EFHD2; EFHD2; SWS1; SWS1] |
Gene, Accession # | [EFHD2], Gene ID: 79180, NCBI: NP_077305, UniProt: Q96C19 |
Catalog # | MBS150334 |
Price | $375 |
Order / More Info | EFHD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |