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Antigenic Specificity | Rac2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to Human Rac2. Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development (1). GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the protein's intrinsic GTPase activity, rendering it inactive. GTP hydrolysis is aided by GTPase activa |
Immunogen | Immunogen: A Fusion protein of human Rac2 |
Other Names | [RAC2; RAC2; EN-7; Gx; HSPC022], [RAC2; RAC2; Gx; EN-7; HSPC022; p21-Rac2] |
Gene, Accession # | Gene ID: 5880, NCBI: NP_002863.1, UniProt: P15153 |
Catalog # | MBS126035 |
Price | $275, $430 |
Order / More Info | Rac2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Wennerberg, K. and Der, C.J. (2004) J Cell Sci 117, 1301-12. 2. Bernards, A. and Settleman, J. (2004) Trends Cell Biol 14, 377-85. 3. Rossman, K.L. et al. (2005) Nat Rev Mol Cell Biol 6, 167-80. |