Nhe-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNhe-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionNhe-1 Antibody: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nh
ImmunogenImmunogen: Nhe-1 antibody was raised against a 17 amino acid synthetic peptide near the center of the human Nhe-1. Buffer: Nhe-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Nhe-1; APNH; NHE1; NHE-1; APNH1; APNH; solute carrier family 9 (sodium/hydrogen exchanger), member 1], [SLC9A1; SLC9A1; APNH; NHE1; NHE-1; PPP1R143; APNH1; NHE1; NHE-1]
Gene, Accession #[SLC9A1], Gene ID: 6548, NCBI: P19634.2, UniProt: P19634
Catalog #MBS150683
Price$375
Order / More InfoNhe-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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