Edit |   |
---|---|
Antigenic Specificity | LAMP1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunocytochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LAMP1 Antibody [Mouse monoclonal antibody recognizes LAMP1 of rat and hamster]. This antibody recognizes LAMP1 of rat and hamster. Lysosome-associated membrane proteins (LAMP1 and LAMP2) are major constituents of the lysosomal membrane. These two proteins have closely related structures with 37% sequence homology. Both are transmembrane glycoproteins localized primarily in lysosomes and late endosomes. Upon cell activation, rapid translocation of intracellular LAMPs to the cell membrane is dependent on a carboxyl-terminal tyrosine-based motif (YXXI). Disruption of the spacing between the tyrosine-based motif abolishes lysosome localization of LAMP1, and the altered protein cycles between the membrane and the endosome. Cell surf |
Immunogen | Antigen: Rat liver lysosome membranes |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS190485 |
Price | $410 |
Order / More Info | LAMP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Lewis, V et al. 1985 J Cell Biol 100: 1839-1847 |