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Antigenic Specificity | MECOM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total MECOM protein. The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human MECOM. |
Other Names | [EVI1; MDS1; PRDM3; MDS1-EVI1; AML1-EVI-1] |
Gene, Accession # | [MECOM], Gene ID: 2122, NCBI: NP_004982.2, UniProt: Q13465 |
Catalog # | MBS9406205 |
Price | $255 |
Order / More Info | MECOM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |