Edit |   |
Antigenic Specificity | ACTR1A (Center), 98-126 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: monkey, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A. This gene encodes a 42.6 kD subunit of dynactin, amacromolecular complex consisting of 10-11 subunits ranging in sizefrom 22 to 150 kD. Dynactin binds to both microtubules andcytoplasmic dynein. It is involved in a diverse array of cellularfunctions, including ER-to-Golgi transport, the centripetalmovement of lysosomes and endosomes, spindle formation, chromosomemovement, nuclear positioning, and axonogenesis. This subunit ispresent in 8-13 copies per dynactin molecule, and is the mostabundant molecule in the dynactin complex. It is an actin-relat |
Immunogen | n/a |
Other Names | [Alpha-centractin; Centractin; ARP1; Actin-RPV; Centrosome-associated actin homolog; ACTR1A; CTRN1] |
Gene, Accession # | [ACTR1A], Gene ID: 10121, NCBI: NP_005727.1, UniProt: P61163 |
Catalog # | MBS9211871 |
Price | $165, $370 |
Order / More Info | ACTR1A (Center), 98-126 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sugarbaker, D.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(9):3521-3526(2008) Petretti, C., et al. EMBO Rep. 7(4):418-424(2006) Casenghi, M., et al. Dev. Cell 5(1):113-125(2003) Carew, J.A., et al. J. Thromb. Haemost. 1(6):1220-1227(2003) Takahashi, M., et al. Mol. Biol. Cell 13(9):3235-3245(2002) |