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Antigenic Specificity | XRCC5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total XRCC5 protein. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radios |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human XRCC5. |
Other Names | [KU80; KUB2; Ku86; NFIV; KARP1] |
Gene, Accession # | [XRCC5], Gene ID: 7520, NCBI: NP_066964.1, UniProt: P13010 |
Catalog # | MBS9401359 |
Price | $255 |
Order / More Info | XRCC5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |