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Antigenic Specificity | TNFSF12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFSF12 antibody detects endogenous levels of total TNFSF12. Description: TNFSF12 Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Belongs to the tumor necrosis factor family. Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q.Subunit Structure: Homotrimer (Probable). Interacts with the angiogenic factor AGGF1/VG5Q.Post-translational Modifications: The soluble form derives from the membrane form by proteolytic processing.Similarity: Belongs to the tumor necrosis factor family. |
Immunogen | Immunogen: A synthesized peptide derived from human TNFSF12 Subcellular Location: Secreted and Cell Membrane. Tissue Specificity: Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain. |
Other Names | [APO 3 ligand; APO 3L; APO3 ligand; APO3/DR3 ligand; APO3L; DR3LG; MGC129581; MGC20669; secreted form; TNF-related weak inducer of apoptosis; TNF12_HUMAN; TNFSF 12; Tnfsf12; TNFSF12 protein; Tumor necrosis factor (ligand) superfamily member 12; Tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207] |
Gene, Accession # | [TNFSF12], Gene ID: 8742, NCBI: NP_003800.1, UniProt: O43508 |
Catalog # | MBS9600263 |
Price | $240, $280 |
Order / More Info | TNFSF12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |