Edit |   |
Antigenic Specificity | CD55 / Decay Accelerating Factor (DAF) |
Clone | [F4-29D9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also |
Immunogen | Immunogen: Human umbilical vein endothelial cells (HUVEC) |
Other Names | [CD55; CD55 Cromer blood group system; Complement decay-accelerating factor; CROM; DAF; Daf-GPI; Decay Accelerating Factor for Complement; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-DAF], [CD55; CD55; CR; TC; DAF; CROM; CR; DAF] |
Gene, Accession # | [CD55], Gene ID: 1604, NCBI: NP_000565.1, UniProt: P08174 |
Catalog # | MBS439460 |
Price | $190, $340, $340 |
Order / More Info | CD55 / Decay Accelerating Factor (DAF) Antibody from MYBIOSOURCE INC. |
Product Specific References | Schlossman S et al. (eds) Leukocyte Typing V. Oxford University Press, Oxford, 1995. Kishimoto T. et al., eds. Leukocyte Typing VI, Garland Publishing, Inc, New York and London, 1997.B.E. Loveland - in Leucocyte Typing VI - Part 6 - Known Non-Lineage CD Antigens - NL11 - CD55 Workshop Panel Report pp519-520, 199 |