MBD1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | MBD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.025 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA), ChIP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal Antibody to detect MBD1 in human samples. Background: MBD1 is a transcriptional repressor that specifically binds to methylated CpG dinucleotides in promoter sequences. MBD1 acts by recruiting a variety of histone deacetylases (HDAC's) and chromatin remodelling factors. MBD1-dependent transcriptional repression is mediated by ATF7IP through the recruitment of factors such as the histone methyltransferase SETDB1. MBD1 probably forms a complex with SETDB1 and ATF7IP which couples DNA methylation to H3K9 trimethylation and represses transcription. |
| Immunogen | Immunogen: MBD1 (Methyl-CpG-binding domain protein 1) synthetic peptide containing a sequence from the N-terminal conjugated to KLH. Positive Control: Western blot: Hela cells, ELISA: peptides, ChIP: U2OS cells. |
| Other Names | [CXXC3; PCM1; RFT; Methyl-CpG-Binding Domain 1], [MBD1; MBD1; RFT; PCM1; CXXC3; CXXC3; PCM1] |
| Gene, Accession # | [MBD1], Gene ID: 4152, NCBI: NP_001191065.1, UniProt: Q9UIS9 |
| Catalog # | MBS840436 |
| Price | $290 |
| Order / More Info | MBD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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