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Antigenic Specificity | CD16 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous CD16 protein. FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. Fc fragment of IgG receptor IIIa encoded by FCGR3A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in FCGR3A have been linked to susceptibility to recurrent viral infections, susc |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse CD16] |
Gene, Accession # | [CD16], Gene ID: 2214, NCBI: P08637.2, UniProt: P08637 |
Catalog # | MBS9700294 |
Price | $250, $250 |
Order / More Info | CD16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |