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Antigenic Specificity | LEMD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2. LEMD3 (LEM domain-containing 3) is a lem-domain containing protein, also known as MAN1, whose loss of function results in disorders characterized by osteopoikilosis, Buschke-Ollendorff syndrome, and melorheostosis. LEMD3 is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against an 18 amino acid peptide near the carboxy terminus of human LEMD3. |
Other Names | [LEM domain containing 3, MAN1] |
Gene, Accession # | [LEMD3], Gene ID: 23592, NCBI: NP_055134 |
Catalog # | MBS9406748 |
Price | $320 |
Order / More Info | LEMD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |