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Antigenic Specificity | ATF5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATF5 antibody detects endogenous levels of total ATF5. Function: Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation (PubMed:10373550, PubMed:15358120, PubMed:21212266, PubMed:20654631). Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 (PubMed:15358120). Important regula |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Widely expressed with higher expression levels in liver. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%) |
Other Names | [Activating transcription factor 5 alpha/beta; Activating transcription factor 5; Activating transcription factor X; AFTA; ATF 5; ATF 7; ATF7; ATFX; BZIP protein ATF7; cAMP dependent transcription factor ATF 5; cAMP dependent transcription factor ATF5; Cyclic AMP dependent transcription factor ATF 5; Cyclic AMP dependent transcription factor ATF5; FLJ34666; HMFN0395; MGC102397; NAP1; NRIF3 associated protein; ODA 10; Transcription factor ATFx; Transcription factor like protein ODA 10; Transcription factor like protein ODA10] |
Gene, Accession # | [ATF5], Gene ID: 22809, NCBI: NP_001180575.1, UniProt: Q9Y2D1 |
Catalog # | MBS9604938 |
Price | $240, $280 |
Order / More Info | ATF5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |