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Antigenic Specificity | FGD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4 |
Other Names | [FYVE, RhoGEF and PH domain-containing protein 4 isoform 3; FYVE, RhoGEF and PH domain-containing protein 4; FYVE, RhoGEF and PH domain-containing protein 4; FYVE, RhoGEF and PH domain containing 4; Actin filament-binding protein frabin; FGD1-related F-actin-binding protein; Zinc finger FYVE domain-containing protein 6] |
Gene, Accession # | [FGD4], Gene ID: 121512, NCBI: NP_640334 |
Catalog # | MBS9405242 |
Price | $320 |
Order / More Info | FGD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |