hCD14 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | hCD14 |
| Clone | [RPA-M1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD14 antigen is a GPI (Glycosyl-Phosphatidylinositol)-linked glycoprotein and has been shown to be critically important in the signaling pathways of TLR (Toll-like receptor). CD14 expression in BC (Bladder Cancer) subpopulation of cancer cells is required for increased cytokine production and increased tumor growth. Furthermore, tumors formed by CD14-high cells are more highly vascularized with higher myeloid cell infiltration. Inflammatory factors produced by CD14-high BC cells recruit and polarize monocytes and macrophages to acquire immune-suppressive characteristics. CD14 is located on the surface of immune response cells in the lungs as well as other organs. Both TLR4 and CD14 genes are codependent with MD2 in their roles as signalers |
| Immunogen | Antigen: hCD14. Immunogen Information: Human PHA-stimulated PBMC were used as an immunogen for this antibody. Conjugation: FITC |
| Other Names | [Myeloid cell-specific leucine-rich glycoprotein], [CD14] |
| Gene, Accession # | [hCD14], Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571 |
| Catalog # | MBS668980 |
| Price | $175 |
| Order / More Info | hCD14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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