Calcineurin A Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Calcineurin A antibody, protein, ELISA kits.
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| Antigenic Specificity | Calcineurin A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, dog, rabbit |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Identifies a band at ~61kD on a WB Scientific Background: Calcineurin is a heterodimeric phosphatase protein, also known as calcium-dependent serine-threonine phosphatase. The structure consists of a catalytic subunit alpha, Calcineurin A (57-59KDa) the active site and a Ca2 binding unit, Calcineurin B (19-20KDa) the regulatory subunit(1). Calcineurin plays a key role in the T-cell response growth and differentiation mechanism, regulating the activation of the Nuclear factor of activated T-cells (NFATc) which are important in the expression of IL-2 genes. Calcineurin has been the target of inhibitors, the novel and structural immune-suppressants antifungal drugs(2). Genetic studies in yeast and fungi established the molecul |
| Immunogen | n/a |
| Other Names | [Alpha isoform formerly PPP2B; Calcineurin A alpha; Calcineurin A1; CalcineurinA; Calmodulin dependent calcineurin A subunit alpha isoform; Calmodulin-dependent calcineurin A subunit alpha isoform; CALN; CALNA; CALNA 1; CAM PRP catalytic subunit; CCN 1], [PPP3CA; PPP3CA; CALN; CCN1; CNA1; CALNA; PPP2B; CALNA1; CALNA; CNA] |
| Gene, Accession # | Gene ID: 5530, NCBI: NP_000935.1, UniProt: Q08209 |
| Catalog # | MBS804979 |
| Price | $415 |
| Order / More Info | Calcineurin A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Rusnak F. and Mertz P. (2000) Physiol Rev. 80(4):1483-521. 2. 2.Hemenway CS. And HeitmanJ. (1999)Cell Biochem Biophys. 30(1):115-51. 3. 3.Fox DS. and Heitman J. (2002) Bioessays. 24(10):894-903. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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