Human ERBB2 / HER2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ERBB2 / HER2
Clone[4E1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b,k
FormatProtein A purified
Size0.05 mg
Concentration0.5 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Human ERBB2. A tyrosine kinase receptor in the EGF-receptor family. ErbB2 does not bind ligand on its own, but acts as an amplifier in heterodimers with ErbB1, (EGFR), ErbB3, or ErbB4. Amplification of the ErbB2 gene and overexpression of ErbB2 protein is associated with breast cancer (~25% of cases), and anti-ErbB2 therapeutics (e. g. Herceptin, an anti-ErbB2 monoclonal antibody) are sometimes effective in treating these cases. Overexpression of ErbB2 has also been indicated as a factor in prostate cancer.
ImmunogenImmunogen Description: Recombinant protein
Other Names[ERBB2 / HER2 (clone 4E1) IHC-plus; ERBB2; C-erb B2/neu protein; CD340; HER2; Herstatin; MLN 19; HER-2; Neu; NGL; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; CD340 antigen; MLN19; p185erbB2; TKR1; Human ERBB2; HER2], [HER2]
Gene, Accession #[ERBB2], Gene ID: 2064, NCBI: NP_004439.2, UniProt: P04626
Catalog #MBS246417
Price$605
Order / More InfoHuman ERBB2 / HER2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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