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Antigenic Specificity | CTLA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.7 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Cytotoxic T-lymphocyte protein 4 Antibody. Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family lingands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory correceptor CD28. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 150-200 on huma CTLA4 protein. Immunoglobulin: IgG. Expression: Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory correceptor, on the cell surface following activation. |
Other Names | [CD 152; CD; CD152 antigen; CD152 isoform; Celiac disease 3; CELIAC3; CTLA-4; Cytotoxic T cell associated 4; Cytotoxic T lymphocyte associated serine esterase 4; GRD4; GSE; ICOS; IDDM12; Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; OTTHUMP00000216623], [CTLA4; CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4] |
Gene, Accession # | [CTLA4], Gene ID: 1493, NCBI: AAL07473.1, UniProt: P16410 |
Catalog # | MBS540634 |
Price | $390 |
Order / More Info | CTLA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |