Human LAP/ TGF beta 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman LAP/ TGF beta 1
Clone[6G14]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Neutr
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DescriptionThis antibody was selected for its ability to detect human LAP TGF beta 1. TGF-beta ligands are initially synthesized as precursor proteins that undergo proteolytic cleavage. The mature segments form active ligand dimers via a disulfide-rich core consisting of the characteristic \'cysteine knot\'. TGF-beta signaling begins with binding to a complex of the accessory receptor betaglycan (also known as TGF-beta RIII) and a type II serine/threonine kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates a type I serine/threonine kinase receptor, either ALK-1 or TGF-beta RI (also called ALK-5). The activated type I receptor phosphorylates and activates Smad proteins that regulate transcription. Use of other signaling
ImmunogenPreparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of LAP-TGFb1. Antigen: Recombinant human LAP TGF beta 1
Other Names[TGFB1; CED; LAP; DPD1; TGFB; TGFbeta], [TGFB1; TGFB1; CED; LAP; DPD1; TGFB; TGFbeta; TGFB; TGF-beta-1; LAP]
Gene, Accession #[LAP/ TGF beta 1], Gene ID: 7040, NCBI: NP_000651.3, UniProt: P01137
Catalog #MBS690382
Price$490
Order / More InfoHuman LAP/ TGF beta 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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