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Antigenic Specificity | Rac2 |
Clone | [AT2G11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rac2 (Ras-related C3 botulinum toxin substrate 2), a small (21 kDa) signaling G protein, belongs to the family of Rho GTPases regulating a variety of biological response pathways that include cell motility, cell division, gene transcription, and cell transformation. Upon GTP loading, a conformational change takes place that allows Rac2 protein to interact with several downstream effectors that ultimately process the information and propagate the signal within the cell, causing changes in the actin cytoskeleton, release of inflammatory modulators and innate immunity. |
Immunogen | Immunogen: Recombinant human RAC2 (1-189aa) protein purified from E. coli |
Other Names | [Ras-related C3 botulinum toxin substrate 2.; EN-7; Gx; HSPC022; Ras-related C3 botulinum toxin substrate 2; EN 7; EN7; HSPC 022; p21 Rac 2; p21 Rac2; p21Rac2; RAC 2; Ras related C3 botulinum toxin substrate 2; Ras related C3 botulinum toxin substrate 3; Rho family small GTP binding protein Rac 2; Rho family small GTP binding protein Rac2; Small G protein.], [RAC2; RAC2; Gx; EN-7; HSPC022; p21-Rac2] |
Gene, Accession # | [Rac2], Gene ID: 5880, NCBI: NP_002863, UniProt: P15153 |
Catalog # | MBS200213 |
Price | $240, $315 |
Order / More Info | Rac2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mizuno T, Kaibuchi K, Ando S, et al. (1992). J. Biol. Chem. 267 (15): 10215-8.; Williams DA, Tao W, Yang F, et al. (2000). Blood 96 (5): 1646-54.; Kinsella BT, Erdman RA, Maltese WA (1991). J. Biol. Chem. 266 (15): 9786-94.; |