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Antigenic Specificity | NLK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3. |
Immunogen | Immunogen: NLK antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 234 and 490 of NLK |
Other Names | [Affinity Purified Rabbit NLK; NLK; NLK; serine/threonine-protein kinase NLK; NLK; nemo-like kinase; DKFZp761G1211; FLJ21033] |
Gene, Accession # | [NLK] |
Catalog # | MBS5312170 |
Price | $485 |
Order / More Info | NLK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |