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Antigenic Specificity | Caspase-9 (Phospho Thr125) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Caspase-9 (T125) Polyclonal Antibody detects endogenous levels of Caspase-9 protein only when phosphorylated at T125. CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascad |
Immunogen | Immunogen: Synthesized peptide derived from human Caspase-9 around the phosphorylation site of T125 |
Other Names | [Rabbit Caspase-9 (phospho Thr125); MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
Catalog # | MBS9701210 |
Price | $130, $220, $325 |
Order / More Info | Caspase-9 (Phospho Thr125) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |