GNAT3 (Center), 78-105 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGNAT3 (Center), 78-105
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThis GNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the Central region of human GNAT3. Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed,
Immunogenn/a
Other Names[Guanine nucleotide-binding protein G(t) subunit alpha-3; Gustducin alpha-3 chain; GNAT3]
Gene, Accession #[GNAT3], Gene ID: 346562, NCBI: NP_001095856.1, UniProt: A8MTJ3
Catalog #MBS9207772
Price$165, $370
Order / More InfoGNAT3 (Center), 78-105 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesFushan, A.A., et al. Chem. Senses 35(7):579-592(2010) Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008) Margolskee, R.F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(38):15075-15080(2007) Jang, H.J., et al. Proc. Natl. Acad. Sci. U.S.A. 104(38):15069-15074(2007) Fehr, J., et al. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 193(1):21-34(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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