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Antigenic Specificity | GNAT3 (Center), 78-105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the Central region of human GNAT3. Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, |
Immunogen | n/a |
Other Names | [Guanine nucleotide-binding protein G(t) subunit alpha-3; Gustducin alpha-3 chain; GNAT3] |
Gene, Accession # | [GNAT3], Gene ID: 346562, NCBI: NP_001095856.1, UniProt: A8MTJ3 |
Catalog # | MBS9207772 |
Price | $165, $370 |
Order / More Info | GNAT3 (Center), 78-105 Antibody from MYBIOSOURCE INC. |
Product Specific References | Fushan, A.A., et al. Chem. Senses 35(7):579-592(2010) Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008) Margolskee, R.F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(38):15075-15080(2007) Jang, H.J., et al. Proc. Natl. Acad. Sci. U.S.A. 104(38):15069-15074(2007) Fehr, J., et al. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 193(1):21-34(2007) |