LC3A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LC3A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human; mouse; rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~14 kDa. Band at 50 kDa is LC3A complex. Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy; once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3A is one of three isoforms which exhibits abundant expression in the heart, brain, liver, skeletal muscle, and testis but is absent in thymus and peripheral |
| Immunogen | Immunogen: Synthetic peptide from the N-terminal of Human LC3A (aa. 1-12). Immunogen Species: Human. Cellular Localization: Cytoplasm; Cytoskeleton; Endomembrane System; Lipid-Anchor; Cytoplasmic Vesicle; Autophagosome Membrane; Lipid-Anchor; Cytoplasmic Vesicle; Autophagosome. Conjugate: Unconjugated. Storage Buffer: PBS, 50% glycerol, 0.09% sodium azide. Tissue Specificity: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. |
| Other Names | [Rabbit Human LC3A; MAP1 light chain 3 like protein 1; Map1lc3a; MAP1BLC3; Autophagy-related ubiquitin-like modifier LC3 A; MAP1LC3A; LC3A; Microtubule-associated proteins 1A and 1B; light chain 3; MAP1ALC3; MAP1A/1B light chain 3 A; MAP1A/MAP1B light chain 3 A; Microtubule-associated protein 1 light chain 3 alpha; LC3; Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; MAP1A/MAP1B LC3 A; ATG8E; MLP3A_HUMAN; MAP1 light chain 3-like protein 1; Microtubule associated proteins 1A/1B light chain 3], [MAP1LC3A; MAP1LC3A; LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3; MAP1A/MAP1B LC3 A] |
| Gene, Accession # | [LC3A], Gene ID: 84557, NCBI: NP_115903.1, UniProt: Q9H492 |
| Catalog # | MBS809454 |
| Price | $390 |
| Order / More Info | LC3A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Tanida I., Ueno T., & Kominami E. (2008) Methods Mol Biol. 445:77-88. 2. He H., et al. (2003) J Biol Chem. 278(31): 29278-87. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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