GRB14 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GRB14 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: GRB14 antibody detects endogenous levels of total GRB14. Function: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.Subunit Structure: Interacts with the cytoplasmic domain of the autophosphorylated insulin receptor (INSR), through the SH2 domain (By similarity). Interacts wit |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm, Golgi Apparatus Membrane, Peripheral Membrane Protein, Endosome Membrane. Tissue Specificity: Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (82%) |
| Other Names | [GRB14 adapter protein; Grb14; GRB14_HUMAN; Growth factor receptor bound protein 14] |
| Gene, Accession # | [GRB14], Gene ID: 2888, NCBI: NP_001290351.1, UniProt: Q14449 |
| Catalog # | MBS9605546 |
| Price | $240, $280 |
| Order / More Info | GRB14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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