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Antigenic Specificity | KRT19 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1, 2). Keratin isoforms demonstrate tissue-and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).Keratin 7 and Keratin 19 have been shown to be present in hepatic and pancreatic progenitor/stem cells (7, 8). |
Immunogen | Immunogen: Recombinant protein of human KRT19 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [KRT19; K1CS; CK19; K19; CK 19; Cytokeratin 19] |
Gene, Accession # | [KRT19], Gene ID: 3880, NCBI: NP_002267.2, UniProt: P08727 |
Catalog # | MBS8503497 |
Price | $310 |
Order / More Info | KRT19 Antibody from MYBIOSOURCE INC. |
Product Specific References | 10. Moll, R. et al. (1982) Cell 31, 11-24. 11. Chang, L. and Goldman, R.D. (2004) Nat Rev Mol Cell Biol 5, 601-13. 12. Ramaekers, F.C. and Bosman, F.T. (2004) J Pathol 204, 351-4. 13. Lane, E.B. and McLean, W.H. (2004) J Pathol 204, 355-66. 14. Zatloukal, K. et al. (2004) J Pathol 204, 367-76. 15. Owens, D.W. and Lane, E.B. (2004) J Pathol 204, 377-85. 16. Iyer, A. et al. (2008) Hum. Pathol. 39, 1370-1377. 17. Meier, K. et al. (2009) Ann Anat 191, 70-82. |