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Antigenic Specificity | GDF-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GDF-5 Polyclonal Antibody detects endogenous levels of GDF-5 protein. GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 5 regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplas |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human GDF-5 |
Other Names | [Rabbit GDF-5; GDF5; CDMP1; Growth/differentiation factor 5; GDF-5; Cartilage-derived morphogenetic protein 1; CDMP-1; Radotermin] |
Gene, Accession # | [GDF-5], Gene ID: 8200, NCBI: P43026.3, UniProt: P43026 |
Catalog # | MBS9703691 |
Price | $130, $220, $325 |
Order / More Info | GDF-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |