SGO1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySGO1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionPlays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensin
ImmunogenImmunogen: Recombinant Human Shugoshin 1 protein (260-439AA) Conjugation: Non-conjugated
Other Names[Shugoshin 1; Serologically defined breast cancer antigen NY-BR-85; Shugoshin-like 1; SGO1]
Gene, Accession #[SGO1], Gene ID: 151648, NCBI: NP_001012409.1, UniProt: Q5FBB7
Catalog #MBS7052889
Price$160, $235
Order / More InfoSGO1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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