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Antigenic Specificity | DUSP11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splic |
Immunogen | Immunogen: Rabbit polyclonal DUSP11 (1) antibody was raised against a recombinate human DUSP11 protein 2-179aa (BC000346). |
Other Names | [dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)], [dusp11; pir1] |
Gene, Accession # | [DUSP11], Gene ID: 100151717, NCBI: NP_001120892.1 |
Catalog # | MBS416747 |
Price | $230 |
Order / More Info | DUSP11 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Chambers,J.C., Zhang,W., Lord,G.M. et al. Genetic loci influencing kidney function and chronic kidney disease. Nat. Genet. 42 (5), 373-375 (2010). |