Edit |   |
---|---|
Antigenic Specificity | DHX58 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of DHX58 protein. DHX58 (DExH-Box Helicase 58) is a Protein Coding gene. Among its related pathways are RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways and Innate Immune System. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is IFIH1. Acts as a regulator of DDX58/RIG-I and IFIH1/MDA5 mediated antiviral signaling. Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1-dependent signaling events. Can have both negative and positive regulatory functions related to DDX58/RIG-I and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on |
Immunogen | Immunogen: Synthesized peptide derived from part region of human DHX58 protein at amino acid sequence of 451-500 |
Other Names | [Rabbit DHX58; Probable ATP-dependent RNA helicase DHX58; Probable ATP-dependent helicase LGP2; Protein D11Lgp2 homolog; RIG-I-like receptor 3; RLR-3; RIG-I-like receptor LGP2; RLR] |
Gene, Accession # | [DHX58], Gene ID: 79132, NCBI: EAW60798, UniProt: Q96C10 |
Catalog # | MBS9708950 |
Price | $130, $220, $325 |
Order / More Info | DHX58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |