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Antigenic Specificity | DISP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of DISP1 are known to exist; this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1. DISP1 Antibody: DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis; mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh. |
Immunogen | Immunogen: DISP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human DISP1. Buffer: DISP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DISP1; DISPA; DISPA; Protein dispatched homolog 1; dispatched homolog 1], [DISP1; DISP1; DISPA; DISPA] |
Gene, Accession # | [DISP1], Gene ID: 84976, NCBI: NP_116279, UniProt: Q96F81 |
Catalog # | MBS151446 |
Price | $375 |
Order / More Info | DISP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |