PP2C alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPP2C alpha
Clone[p6c7]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG2b, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionProtein phosphatase 2C (PP2Calpha) is a Mn2+ - or Mg 2+ -dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNk MAPk pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2Calpha, the prototypical member of the PPM family.
ImmunogenImmunogen: Recombinant human PP2Calpha (1-382aa) purified from E. coli
Other Names[Protein phosphatase 1A (formerly 2C) magnesium-dependent alpha isoform; PDP1; PDP; PPM2C; PP2C alpha; Protein phosphatase 2C; PDP 1; EC 3.1.3.43; Pyruvate dehydrogenase phosphatase catalytic subunit 1; PDPC 1; Pyruvate dehydrogenase acetyl-transferring-phosphatase 1; PPM1A; Protein phosphatase 1A (formerly 2C); ppm1a; FLJ42306; MGC9201; PP2CA; PP2Calpha; PP2C-alpha; protein phosphatase Mg2+/Mn2+ dependent 1A], [PPM1A; PPM1A; PP2CA; PP2Calpha; PP2C-ALPHA; PPPM1A; PP2C-alpha]
Gene, Accession #[PP2C alpha], Gene ID: 5494, NCBI: NP_066283, UniProt: P35813
Catalog #MBS200003
Price$240, $315
Order / More InfoPP2C alpha Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLin X, et al., (2006) Cell. 125 (5): 915-928; Duan X, et al., (2006) J Biol Chem. 281 (48):36526-32
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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