JARID1B (N-term), 192-224 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | JARID1B (N-term), 192-224 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This JARID1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B. Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. |
| Immunogen | n/a |
| Other Names | [Lysine-specific demethylase 5B; 11411-; Cancer/testis antigen 31; CT31; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; PLU-1; Retinoblastoma-binding protein 2 homolog 1; RBP2-H1; KDM5B; JARID1B; PLU1; RBBP2H1] |
| Gene, Accession # | [KDM5B], Gene ID: 10765, NCBI: NP_006609.3, UniProt: Q9UGL1 |
| Catalog # | MBS9206593 |
| Price | $165, $370 |
| Order / More Info | JARID1B (N-term), 192-224 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kim, J., et al. Biochem. Biophys. Res. Commun. 401(3):412-416(2010) Krishnakumar, R., et al. Mol. Cell 39(5):736-749(2010) Yao, W., et al. Biochem. Biophys. Res. Commun. 396(2):323-328(2010) Roesch, A., et al. Cell 141(4):583-594(2010) Hayami, S., et al. Mol. Cancer 9, 59 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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