Edit |   |
---|---|
Antigenic Specificity | CACNA1C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CACNA1C antibody detects endogenous levels of total CACNA1C. Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death (PubMed:29078335). The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omeg |
Immunogen | Immunogen: A synthesized peptide derived from human CACNA1C, corresponding to a region within C-terminal amino acids. |
Other Names | [voltage-dependent L-type calcium channel subunit alpha-1C isoform 18; Voltage-dependent L-type calcium channel subunit alpha-1C; voltage-dependent L-type calcium channel subunit alpha-1C; calcium voltage-gated channel subunit alpha1 C; Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; Voltage-gated calcium channel subunit alpha Cav1.2] |
Gene, Accession # | [CACNA1C], Gene ID: 775, NCBI: NP_000710.5, UniProt: Q13936 |
Catalog # | MBS9603803 |
Price | $240, $280 |
Order / More Info | CACNA1C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |