DC-SIGN [5D7] Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DC-SIGN [5D7] |
| Clone | [5D7] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum. |
| Immunogen | Immunogen: A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN. Buffer: DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [DC-SIGN [5D7] : CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CD209 molecule], [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1] |
| Gene, Accession # | [CD209], Gene ID: 30835, NCBI: Q9NNX6.1, UniProt: Q9NNX6 |
| Catalog # | MBS150015 |
| Price | $375 |
| Order / More Info | DC-SIGN [5D7] Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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