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Antigenic Specificity | MAP2K6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MAP2K6 protein. Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human MAP2K6. |
Other Names | [Dual specificity mitogen-activated protein kinase kinase 6; EC 2.7.12.2; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 6] |
Gene, Accession # | [MAP2K6], Gene ID: 5608, NCBI: NP_002749.2, UniProt: P52564 |
Catalog # | MBS9404376 |
Price | $200, $255 |
Order / More Info | MAP2K6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |