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Antigenic Specificity | Chicken CD45 |
Clone | [LT40] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgM kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Chicken CD45 (Mr 190 to 215-kDa). Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45.1 Levels of CD45 expression detected by MAb LT40 in the avian thymus are heterogeneous with approximately 90% of thymocytes expressing fourfold higher levels of surface CD45 (CD45hi) than do the remaining 10% (CD45lo) of thymocytes. The CD45lo population contains exclusively thymocytes with the CD3-CD4-CD8lo phenotype characteristic of the immediate precursors to the CD3- CD4+CD8+ thym |
Immunogen | n/a |
Other Names | [Mouse Chicken CD45 - Purified, Unlabeled; Mouse Chicken CD45], [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45] |
Gene, Accession # | Gene ID: 5788, UniProt: P08575 |
Catalog # | MBS673896 |
Price | $305 |
Order / More Info | Chicken CD45 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Paramithiotis, E., L. Tkalec, and M.J.H. Ratcliffe. 1991. J. Immunol. 147:3710. |