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Antigenic Specificity | RANBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RANBP1 antibody detects endogenous levels of total RANBP1. Function: Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426). |
Immunogen | Immunogen: A synthesized peptide derived from human RANBP1 Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (92%), Sheep (92%), Rabbit (92%), Dog (100%) |
Other Names | [HTF9A; RAN binding protein 1; Ran specific GTPase activating protein; Ran-binding protein 1; Ran-specific GTPase-activating protein; RANBP1; RANG_HUMAN] |
Gene, Accession # | [RANBP1], Gene ID: 5902, NCBI: NP_001265568.1, UniProt: P43487 |
Catalog # | MBS9608751 |
Price | $240, $280 |
Order / More Info | RANBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |