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Antigenic Specificity | TYROBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of SK-SEP1 cell line, using TYROBP antibody. This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopa |
Immunogen | Immunogen: Recombinant protein of human TYROBP |
Other Names | [TYROBP; TYRO protein tyrosine kinase-binding protein; TYRO protein tyrosine kinase-binding protein; TYRO protein tyrosine kinase binding protein; DNAX-activation protein 12; Killer-activating receptor-associated protein; KAR-associated protein] |
Gene, Accession # | [TYROBP], Gene ID: 7305, NCBI: CAG46999.1 |
Catalog # | MBS4150358 |
Price | $385 |
Order / More Info | TYROBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |